We reviewed 111 patients with prostatic cancer during a 20 year period from October 1973 to July 1993, retrospectively.
The patients age ranged from 55 to 86 years with a mean of 70.7 years. The major presenting symptom were urinary retention(45.9%), prostatism(37.9%), gross hematuria, and bone pain. On digital rectal examination, 20 patients had a hard nodule on
the
prostate, and 2 patients had multipe nodules. There were stage A in 23 cases, stage B in 15, stage C in 8, and stage D in 65. Among 65 cases of stage D. stage Do and stage D2 were 30 and 31, respectively. Hydronephrotic changes were found on
I.V.P.
in
13 patients. The site of metastasis in stage D2 patients(31 cases) were bone 29, lung in 2 cases. The combined Gleason score were 2-4(well differentiated) in 15 cases, 5-7(moderately differentiated) in 51 cases, and 8-10(poorly differentiated) in
45
cases. For the treatment of 111 patients, conservative treatment(TUR-P) was performed in 33 patients, radiation therapy in 8 patients, endocrine therapy (orchiectomy or DES) in 70 patients. Fifty nine cases were followed for mean 52.3 months.
Five
year
survival, there was 92% for low combined Gleason(2-4), 78% for intermediated group(5-7), and 45% for high grade(8-10). Six cases with clinical stage A, B were proved to be alive for 10 years. Of the 13 cases with clinical stage D1, D2 11 cases
died
and
their mean survival was 23 months.
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